Built and settled beginning in 1673, after the original settlement (now known as Panama Viejo) was destroyed by British pirates, was a slum for many years but is now packed with charming, cleaned up colonial architecture, several historical sites and museums (including one dveoted to the canal), and a slew of cafés, bars, shops, galleries, restaurants, and boutique hotels.

Read more in Tripatini contributor Keith Kellett´s post Panama: The Canal & the Capital.