Harry D.
You've of course heard of Tikal, Antigua, and Guatemala City. But 2,330 metres (7,644 feet) up in the western highlands just two or so hours from the capital, this country’s second largest city (pop. around 225,000) is a dynamic, untouristy trove that not only has a lot to offer on its own terms but is also a great jumping off point for other attractions, including Lake Atitlán and several of Guatemala's awesome ecotourism wonders.
Elijah-Lovkoff
Originally the pre-Columbian Mayan city